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Stem Cells to Re-attach Teeth

By: Ian Murnaghan BSc (hons), MSc - Updated: 25 Nov 2018 | comments*Discuss
Stem Cells Re-attach Teeth Tooth Grow

Tooth loss affects people in Britain and elsewhere around the world. While modern dentistry offers a number of options for missing teeth, these still take time and can be costly.

Helping Treat Tooth Loss

A new experiment, however, suggests we may one day be able to re-attach teeth by using stem cells. People can lose their teeth in many ways but gum disease is a significant problem for many people.

There are estimates that as many as eighty percent of adults suffer from some degree of gum disease. This infection is a very serious one that can ultimately lead to tooth loss later on in life. Other people may suffer trauma and lose their teeth.

A New Way to Battle Tooth Loss

In this recent study, researchers took stem cells from a specific ligament in the molars of mice. They treated these stem cells in the laboratory and then used them on barren molars. Once these molars were inserted back into the empty sockets of the mice, they eventually anchored back into the space.

Healthy Tooth Attachment Using Stem Cells

It was at around two months that stem cells began to create new attachments from the tooth to the bone. The result was that the attachment was a solid one and the re-attachment was considered a success.

As researchers looked at the tissue, they could see that surrounding the tooth were fresh ligament fibers and a substance called cementum, which is another part of a normal tooth connection. When compared to tooth molars that were re-attached without these stem cells, the attachment was unsuccessful.

Growing Teeth Using Stem Cells

Previous studies have looked at ways to grow teeth using stem cells. In another study, researchers used special tooth-shaped scaffolds along with specific proteins and growth factors to draw in stem cells and develop the bone. Perhaps most incredible was the fact that this growth occurred in only nine weeks. It’s a new direction of stem cell studies that can offer another potential option for people who lose their teeth.

Even more unique is that it works by attracting stem cells already in the person’s body rather than requiring an injection of stem cells from a donor. The quick recovery time and natural use of the body’s own resources would make this a particularly attractive dental treatment one day.

A Novel Treatment for Tooth Loss

For the study that looked at re-attaching teeth using stem cells, it is the first time that such a treatment has successfully been performed. It is thought that it would be valuable for those people who have experienced trauma and lost a tooth. This might be an athlete or someone who is in a car accident. In particular, it may be used for the significant numbers of people who suffer from severe gum disease and experience tooth loss.

Dental Implants Continue as a Treatment of Choice

Until then, there are still dental implants and these are largely successful. But a new stem cell treatment that utilises the body’s own resources to quickly re-attach teeth would be a welcome addition to dental options for missing teeth.

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What alternative isto healing ainfection from a touth who have rooted canal(25) ? In what condition is possible /probable to use stem cell to regenerate infected area ? Thanks for your help
Alex - 25-Nov-18 @ 9:14 PM
Sir;please update us regularly the current status of this technique..when It will be available?Is it true?why the researchers taking so much time?
Babu - 9-Nov-18 @ 3:44 AM
Please notify me when this facility available....iam from India....
Biki - 25-Oct-18 @ 3:56 AM
Thanks sir.it is very good application in dental ...I had lost my front upper incisors by accidentally....so I kindly requested to u when this facility available please notify me.......this is incredible in regrowth our tooth by stem cell using.... very excited...
Biki - 25-Oct-18 @ 3:54 AM
I would be interested in more information, and if you have a trial for periodontal disease, involving stems cells, interested in knowing more.
Judy - 4-Oct-18 @ 1:02 AM
I have a tooth missing in the front.....it's Irritating!! I'm told it will cost 6500 to regrow bone and put in an implant. I don't have that kind of cash and can't get credit due to my recent divorce.If you have a trial in South Carolina i would like to try and see if it works. Thank you for your time and Research into this awesome stem cell technology.
Marc - 26-Sep-18 @ 12:40 AM
I am interested, please send me info.
none - 5-Sep-18 @ 3:44 PM
I had my Jaw broken in 1983 by an abusive partner, whom I subsequently left. Having my teeth wired together to hold my jaw in place led to problem in my gums and resulted in tooth loss and movement. I’m suffering to this day from a collapsed bite and front tooth erosion from chewing in the wrong place. I would be most grateful and appreciative if I were to have the good fortune to be granted a trial in this new venture. Many thanks and Best Wishes Bee
Bee - 19-Aug-18 @ 1:54 PM
sir i have lost some teeth b cos of injury and trauma.i really want to regrow my loss teeth,kindly give me latest information about stem cell dentistry
rb - 21-Jul-18 @ 12:18 AM
I'd love to volunteering for stem cell therapy on broken and damaged teeth.
Me - 14-Jul-18 @ 12:49 AM
I'm a 61 yr old male. My crowns are getting old and two have totally decayed under the crown, broke off and had to be extracted. Two others are scheduled to be pulled from the same decay under the crown and infected root canal. I'm healthy and on no medications or alcohol, and no gum disease. I would be excited to volunteer for stem cell trials.
John - 12-Jul-18 @ 4:51 AM
Hi! I would love information on getting into one of the trials! My tooth loss started with an MVA. Ever since that accident, my teeth just chip away slowly. I have no insurance so I make the partial I have work. I am scared to death that my only tooth up front is probably getting ready to go also. It is such a mental hardship missing teeth. I work in the medical field, still actively play softball from feb-nov. I try not to speak too much due to my tooth loss and I hate it because I love people and to talk. Please help me get into a trial!!!
Dani - 6-Jul-18 @ 7:17 PM
Hi could you send me info please..
Berty - 6-Jul-18 @ 2:12 PM
I really do wish this could move forward.I am 36 and have lost all of my teeth from poor dental care, abuse and the partials they used had metal wires that destroyed what teeth did remain. I have went without teeth or dentures for 6 years because i cannot wear them or eat with them.It is extremely embarrassing especially at my age.I have noway of ever affording implants because they make them so expensive and insurance does little to help. This would be life changing for so many in the world currently let alone the amount of peple it could impact overtime.I would definatly do anything to be in a trial so i can feel like me again. It is too bad these things take so long to move forward to a useable point.
Sally - 5-Jul-18 @ 6:20 AM
I am 52 & lost all my teeth due to car accident 30 years ago, I have healthy gums and do not wear dentures. Having no teeth causes you to eat less healthy foods mostly and really has an impact on your social life. haven't smiled for years... It's hard to believe that we can put people in space, grow organs in a lab and clone animals (and I am sure people in secret government labs) yet we can't find a way for people to re-grow teeth. It would be amazing to have a set of real teeth again. If someone needs volunteers for a promising new procedure I would volunteer or a some type of implant trial. Doctors and scientists PLEASE work on this......
Mike - 27-Jun-18 @ 7:39 AM
I am very i terested in volunteering fir stem cell therapy on broken and damaged teeth. Also for Fibromyalgia painand Arthritis. As well as aging. I am 65 but look younger. I truly would like to be in a study as a Canadian. Thank you
CuriousLin - 4-Jun-18 @ 7:25 AM
muje new teeth ugaane ki dwai chahiye please help me .
pushpa - 26-May-18 @ 2:05 AM
@Dior - it takes time to be able to find out if the treatment is safe and to trial whether it has no long term repercussions.
Ade - 22-May-18 @ 12:36 PM
I can not understand why they talk about this technique for years and nothing happens !!! Wake up !!!
Dior - 21-May-18 @ 10:45 PM
Am from India my tooth became sensitive I would like to replace my tooth using stem cell method. When it is going to launch in India. Please let me know.
Nithya - 15-May-18 @ 12:44 PM
I have had dentures for years. I wish the dentist had have told me not to get them. I hate the constant saliva build up. I only wear them when I walk out the front door because they feel horrible. They have affected me emotionally. I have very little self confidence because of them. Dental implants are so expensive. This would be fantastic and would love to sign up for the trials
Linda - 12-May-18 @ 10:37 AM
My toorh loss journey started in my 30s with a car accident.Partial dentures wore at my exising teeth, with the result of full top ill fitting dentures and painful bottom teeth. They have stopped me eating causing poor health.I have no confidence for socialising and live a miserable life.I am unable to afford implants so for me, this new technology would be like being reborn.Excellent prospect.
Milly - 9-May-18 @ 3:08 PM
I didn’t go to the dentist growing up because my parents couldn’t afford it. I went for the first time in my 20s. My teeth are terrible. I’m missing 3 and getting ready to need a 4th removed. I’d pay to be on a trial for stem cell teeth regrowth. $3-4 thousand bucks? I’m in. Much better than a bunch of implants at my age of 35.
Ams - 7-May-18 @ 12:13 PM
Hi , I am so desperate I have been loosing my teeth at a very rapid rate due to dentist not caring enough to help it is all about the money with them I dont even have a gum disease just receding gums.I would move heaven and earth to have this trial , please consider my I am will pay for it as well. many thanks . Blackie
Blackie - 3-May-18 @ 12:29 PM
i have two rootcanels and one tooth that aches. i relalize that so much disease in our bodies start with our mouth. Hence keeping my mouth healthy is really important to me. Im so ready to heal ans get to be a first in stem cell theray.
Carol Conrad - 29-Apr-18 @ 5:24 AM
Excellent work ! Im very interested in how far this has come. Does it require open flap surgery?. How is it applied ? Will there be human trials ? I have gum loss , bone loss, connection fibre loss. Still have my teeth , only just. The're hanging on a thread and can't use most of them. I am also willing to participate in any trials.Please contact me. Regards Chris.
Chris - 29-Apr-18 @ 12:31 AM
Hi could you keep updated on this research please
Bert - 14-Apr-18 @ 7:43 PM
I would like to be considered for this trial and treatment. I have had chemotherapy for stage 4 cancer and have lost many teeth. I am not eligible for dental implants because of my disease and severe gum disease. I am willing to pay towards the cost of this treatment. Thank you for your consideration.
Lou - 10-Apr-18 @ 11:20 PM
I am 32 years old and my teeth are falling apart..i don't have the money to go to the dentist and its casuing so much pain and also its just extremely depressing...I would be over the moon to be able to participate in this trial please contact me if possible...thanks for your consideration. -Julia
Jules - 5-Apr-18 @ 6:16 PM
I need this stem cell treatment asap. How do I get it and where. I'll travel anywhere
James - 30-Mar-18 @ 8:51 AM
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