Home > Uses for Stem Cells > Stem Cells for Stroke Victims

Stem Cells for Stroke Victims

By: Ian Murnaghan BSc (hons), MSc - Updated: 24 Jun 2018 | comments*Discuss
 
Stem Cells Stroke Studies Clinical Brain

Brain damage that results from stroke is an enormous challenge to address for people around the world. That's why research into stem cell therapies for stroke victims is so vital to reduce the devastating effects of stroke on its victims.

Stem Cell Study

A new study is set to go ahead in the United Kingdom (UK) to find out if stem cells are able to repair brain damage suffered by stroke victims (see bottom of page for update). The company is aiming to begin clinical trials in the first half of this year on twelve patients. While there has been some preliminary success on stem cell treatments for similar brain damage, this new study will address a condition that has widespread effects.

Designing the Study

In this British study, stroke victims will have neural stem cells injected into their skull. While it sounds quite graphic, the injections will involve a very fine syringe and will target the parts of their brains that have been more severely affected by the stroke.

Researchers hope that these neural stem cells will then develop into healthy brain tissue as well as neurons and other related, supportive structures in the brain. If the study proves successful, it will mean that the stroke victim's brain will have newly restored connections – a better, healthier brain network, so to speak.

Taking Animal Studies to Humans

So far, we have also seen positive results from studies in mice, where they were able to regain brain functioning following injury to the brain. These kinds of animal experiments have prompted the need for human studies and it is hoped that this new clinical trial will provide similar – or greater – success.

One interesting aspect of this kind of study is that once the stem cells are injected, we don't know exactly how they work and develop in the brain. We can measure the outcomes of the procedure but we can't actually track everything that happens once the neural cells are injected. So, we don't know where they travel exactly or how they change and develop.

Scans taken regularly can show brain functioning and activities after the treatment but the precise process by which the brain 'heals' is something that for now, will remain a mystery. At best, we can hope for a positive result by whatever physical mechanism occurs and perhaps in the future, we will also be able to observe the pathway itself by which stem cells help stroke victims.

Awaiting Study Results

Many of us will be anxiously awaiting the results of the study, which provides hope for the many people who have suffered from brain damage due to a stroke. For now, however, the best thing the rest of us can do is to focus on preventative strategies to reduce the likelihood of suffering from a stroke.

With stroke being as prevalent as it is, it's likely most of us will either suffer from a stroke at some point in our lifetime or we will know someone who does suffer from one and possibly has brain damage to some degree as a result. Hopefully, the new British study will offer hope for everyone who is affected by stroke or will be one day.

Update: A pilot study by Imperial College London infused particular types of stem cells that stimulate growth, known as CD34+ into damaged sections of the brain. All the five patients showed improvements in clinical measures of disability. While these trials are still in their very early stages it shows promise for future clinical trials.

You might also like...
Share Your Story, Join the Discussion or Seek Advice..
[Add a Comment]
My husband had a 2nd stroke 2017 and it had broken his way of life. He has vision problems,speech problems, right side paralysis and his walking is very limited. I am his full time care giver and he is very depressed. He has asked about this before his second stroke but I had very little information. He would be grateful to have some of his skills back again. If you could help us please notify us
jerry wright - 24-Jun-18 @ 3:55 AM
Hi, I am a 58 year old Male who suffered a massive stroke when I was 44 years old June 20. 2004 I was in real bad shape, my right side was 80% paralyzed, my right arm was 99% paralyzed, couldn't walk, talk, swallow, or use my right arm at all. 6 months of very intense therapy I began to recover somewhat. I am walking, talking, and have limited use of my right arm, I walk with a noticeable limp and can not straighten my right arm all the way out. I've been doing a little reading about stem cell research, and it's benefits. I would like to be considered for any ongoing test or treatment that may help me to regain some, most, or all my motor functions. Thank You very much, Roger
Roger - 13-Jun-18 @ 2:42 PM
I would like to benquire updated with information I have suffered a hemmoragic Stroke a little over two years aho
Emer - 4-Jun-18 @ 8:17 PM
I suffered from cva stroke on 30th jan 2018 it affected my right hand side. Leg and arm i was so determined. To walk again i am walking with splint. And walking stick. But i had a sub lux. Which stopped. Progress with my hand i had a steriod injection to help and my hand. Is still. Non functioning and i am desparate.Id do anything to get ir to work im positive i can fight this. But. I would. Like to take part in your trial please consider me. I want a near normal life back if i Can
Maggie - 2-Jun-18 @ 9:28 AM
In February 2017 I suffered a serious stroke and still have a paralysed left arm, which has affected every aspect of my life.I would be very interested to take part in stemcell treatment trials or undergo approved treatment at a private clinic.Such clinics exist in India, Thailand and parts of Eastern Europe.I have no wish to undergo treatment at any of these places.Is there a licenced clinic in the uk or Ireland offering stemcell treatment for post stroke paralysis?
Hanny - 31-May-18 @ 5:10 PM
My dad had a stroke and it has effected his left aside with cognitive and nerogocial issues.He did everything to help people before and now can't do anything.I asked him to see an Alexander Teacher and do yoga (traditional) but refuses.I try and encourage swimming and repetive exercises but it's like he has given up and says away as a real mans man.Now he gets emotional and upset.Something he would not do and is embarrassed .The stem cell treatment would be amazing for everyone concerned and if trails come up ,please consider my dad also.His grandson loves him dearly and has a lot of respect for him but says he is not the person he once was'.Making life choices he wouldn't normally do .It is like a different person and very hard on the family .Thanks for reading.Melanie
Mel - 29-Apr-18 @ 10:05 AM
Had a stroke 3 years ago right hand side affected. Cannot use right hand. Can walk without walking stick. Eyes have been badly affected. Any help thanks
zanussi - 30-Mar-18 @ 11:54 AM
I had a cerebral Hemorrhage3 years ago.It affected my left hand and leg.I walk but not perfect like it was before. I have almost recovered my left hand but left with spascities , tingling and shoulder becomes heavy. I'm in Belgium.Can I benefit fromstem cell therapy and which European hospitals are conducting chronic hemorrhage stroketrials ? Pleasehelp !!!!
James - 25-Mar-18 @ 4:05 PM
Hi im 48 i had a hemorajic bleed strokeon my right side, at presentmy condition is i can walk without a stick but cant use my left hand, can stem cell treatment help? If you can advise please thanks.
Taff - 22-Mar-18 @ 3:29 PM
I m a 52 yr old man who had a stroke in September 2017. This has left me with left sided weakness. I have never smoked and drink very little alcohol I used to jog 3 times a week. Please can you consider me for stem cell treatment.
dave - 15-Mar-18 @ 7:23 PM
My husband Bob suffered a cerebral hemorrhage 2011.He has rt side deficits & aphasia.He is remarkable as he drives an adapted car.We try to live a normal life but if he could get any return of his rt arm & more strength to his rt leg.it would be his/our ultimate wish.We live in the US & have no problem traveling to the UK.
Sue - 23-Feb-18 @ 8:48 PM
I had a hemorrhagic stroke on June 13 2017 .I walk with a walker and brace. Go to PT and feel like I have platued . I was almost accepted into the Stanford/ UCSF trials but they are only doing eschemic stroke at this time . I am suffering from depression Would like to be included in your trial.
Rolando - 20-Jan-18 @ 5:52 PM
Had an eschemic right side stroke in 2009. Left side debilitated. Shoulder (subluxation) particularly affected, so much so it has become completely frozen and is having serious consequences on the rest of my body.It’s now affecting my right (good) side of my body. Was walking with a stick but can’t do it any more because my body has stiffened up. I am in constant pain. getting absolutely no sleep at night. Am at the end of my tether. I think I would benefit from stem cell treatment.
Berna - 18-Jan-18 @ 12:10 PM
How do I get stem cell treatment for my wife, who is a 59 year old stroke survivor with debilitating left side weakness and some cognitive impairment?
John v8 - 9-Jan-18 @ 2:31 PM
I am paralyzed left hand and fingers. Is there any way you can help me? I want to enjoy my grandbabies. I'm about ready to hive up, I believe and pray god has an answer for me
Mary - 4-Dec-17 @ 2:41 PM
I suffered a left-side Stroke on June 2, 2015 while jogging after work. Today I am wheel-chair bound, although I can use a platform walker.I now drive a modified Van, and live as independently as I can.Are Stem Cells a possibility for me?I was a swimmer and runner, and miss them dearly.What can I do to improve?
George - 3-Dec-17 @ 6:01 PM
Hii had a hemorJic stroke bleed on my right side of brain fell down, i can walk ok but cant use my left hand is there any stemcells trials puthere?
Taff - 18-Oct-17 @ 2:43 PM
I am a w oman of 66 y ears.In 2013 I had a stroke with as result a homonymous hemianopia right.C ould a stem cell treatment help me please ?Thanks
Lieve - 26-Jun-17 @ 1:20 PM
Suffered a hemorrhagic stroke in 2017 January l leaving me with left side weakness is there any case study that I might be eligible for stem cell please contact
Fab - 22-Apr-17 @ 2:03 AM
I suffer from right side hemorrhagic stroke the left my left side weakness one of the clinicals stem cell trial studies I may be eligible to participate it I hadin in 2017 January
Fab - 22-Apr-17 @ 2:01 AM
Had a stroke in April 2016 at the age of 72. I have recovered most of my functions but speech and short term memory are impaired. Speech is particularly annoying, as I am a broadcaster. Depth, resonance & power are all diminished and it feels as though my vocal chords are strangulated. I would willingly volunteer to be a research subject. I live in France.
daveboys - 14-Feb-17 @ 2:54 PM
Jackie - Your Question:
Hi, had my third stroke in 1994 at the age of 21, now I'm 43 and find my movement getting worse and wondered if I'd be eligible for stem cell therapy? My last stroke took my right side and although I have gained enough movement to walk aided with an AFO I would love to get more back and not be dependent on crutches or the help of others. Would I qualify for a clinical trial?Many thanksJackie

Our Response:
You would have to keep an eye on the NHS trials, link here. I hope this helps.
ExploreStemCells - 13-Feb-17 @ 12:36 PM
My son has a significant other who stroked at 49. Left side paralysis. Very verbal but she has leftside vision limits. The right 'dead' part of brain removed due to swelling after first operation. Question: In the absence of the right brain section removed, can stem cell therapy work to stimulate remaining brain matter to help repair affected side? She is in long term facility. Thank you for your response.
Jay - 12-Feb-17 @ 6:10 PM
Hi,had my third stroke in 1994 at the age of 21, now I'm 43 and find my movement getting worse and wondered if I'd be eligible for stem cell therapy?My last stroke took my right side and although I have gained enough movement to walk aided with an AFO I would love to get more back and not be dependent on crutches or the help of others. Would I qualify for a clinical trial? Many thanks Jackie
Jackie - 12-Feb-17 @ 11:49 AM
I'm writing on behalf of my twin brother. He has unfortunately had air go to the brain and also clots, the story is to long to write and he is currently in ICU having been their for the last 6 weeks. We are running out of options and time. Please email if you wish to know more. Kind regards C
We are running out o - 14-Jan-17 @ 11:39 PM
I have been following stem cell therapy for stroke with interest and have volunteered for clinical trials with no luck.Usually I do not even receive an acknowlegement.I have been told by my neurologist that I suffered 'the wrong' type of stroke.This perplexed me until it was explained that in stroke research ischemic strokes tend to be considered first due the frequency of them compared to haemmorhagic strokes. My brain exploded 4 years ago whilst I was pregnant leaving me with a dense left hemi and I remain mostly paralysed down my left side but the fatigue is now my biggest enemy.I would happily send my brain to researchers in a pickling jar if they could only restore a little more function.
Lucy - 13-Jan-17 @ 9:42 PM
I suffered a mild stroke on 27 Dec 2014, 57 years old at the time.Everything is functional but my vision was impacted somewhat.Vision is just a little blurrey.My quality of life could be so much better with just a little improvement in my vision. Is anybody working on vision issues after stroke.I assume stem cells could possibly help?
Jimmy - 27-Dec-16 @ 6:27 AM
Hi, i was wondering how could i take part of the trail, im 28, had the stroke for two years after being stabbed in the neck by a domestic voilence ex partner.. im keen to take part of the clinical trail thank you x
Burnettechick - 5-Nov-16 @ 11:36 PM
In April 1997, I just turn 19, I had my first procedure, (an embolization) to fix an AV Malformation on my motorstrip on the right side of my brain.During the procedure there were complications and swelling.I had a severe stroke and woke up on the operating table with my left side paralyzed. The past 19 years have been challenging. I got some movement back up until I turned 30c then my left and and left arm started getting very spastic and losing function. And now at 38 my left side is about 75% paralyzed.Are there any clinical trials available anywhere for me to participate in?
Dmar2480 - 28-Sep-16 @ 11:06 AM
I suffered a stroke 2 years which left me with left sided heminopia.Any stem cell trails into vision loss.
Steve - 20-Sep-16 @ 12:01 PM
Share Your Story, Join the Discussion or Seek Advice...
Title:
(never shown)
Firstname:
(never shown)
Surname:
(never shown)
Email:
(never shown)
Nickname:
(shown)
Comment:
Validate:
Enter word:
Topics
Latest Comments
Further Reading...
Our Most Popular...
Add to my Yahoo!
Add to Google
Stumble this
Add to Twitter
Add To Facebook
RSS feed
You should seek independent professional advice before acting upon any information on the ExploreStemCells website. Please read our Disclaimer.