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Stem Cells and Autism

By: Ian Murnaghan BSc (hons), MSc - Updated: 9 Sep 2020 | comments*Discuss
Stem Cells Autism Model Safe Disease

There is still much we do not know about how autism develops, which makes it more challenging to find new treatments and ways of addressing the disorder. Recently, however, stem cells have shown promise in helping safely develop treatments for autism.

What is Autism?

Autism is a disorder that relates to a person’s neural development. Its classic symptoms include abnormal social interaction and difficulties with normal communication. Behaviours shown by autistic children, for instance, may be antisocial ones.

It is thought that autism interferes with normal information processing because it changes the way that a person’s nerve cells communicate. We still don’t know exactly how and why this occurs although there are numerous links.

What Causes Autism?

It is believed that there is a strong genetic basis for autism although other factors are also suggested to play a role. These include environmental causes or exposure of the mother to toxins.

With the number of people diagnosed with autism continuing to rise, there is more attention being given to the disorder and how we can help those who are diagnosed with autism while preventing its occurrence in the first place.

Using Stem Cells to Study Autism

More recently, studies have focused on better ways to learn about autism. By using stem cells, they have been able to engineer neurons in a way that we now have a human cellular model. This model is a safe way to study how autism develops in the brain.

Rett Syndrome Patients

Researchers obtained the stem cells from adults who have Rett syndrome, which shows similarities to autism and is a major developmental disorder. Given that Rett syndrome is such an extreme case, researchers thought it was ideal to study autism. If they were able to understand what happens with Rett syndrome, they could better understand other developmental disorders such as autism.

Stem Cells for Safer Testing

The benefit of a cell model like this one is that it’s a safe way to test out drugs and other therapies to see if they can provide any potential benefits for people with autism. While it’s common to test on animals, in a disorder such as autism, there are additional challenges.

With something like autism, much of the diagnosis of the disorder comes from behavioural manifestations. In this sense, it is difficult because we can’t see the dysfunctional social interactions and problems with communication that are characteristic of autism.

Without animal testing first, it would mean doing any drug testing in humans, which is significantly more dangerous. The key benefit with the cell model is that we avoid these risks.

Positive Results With Stem Cells

Researchers treated the stem cells and triggered them to differentiate into neurons, but found these neurons had abnormalities we would not see in a neuron from a healthy person. These neurons were smaller and didn’t have the normal number of synapses, which are important for neurons to communicate. When these cells were treated with drugs that help autism symptoms in mice, however, these abnormalities were reversed.

Finding Better Treatments Using Stem Cells

While the study results do not completely prove it will work the same in humans, results are promising and do suggest the neurons can benefit. This use of stem cells as a safer model for testing will also help us perform similar testing for other diseases, giving hope to people with autism or other developmental disorders.

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Do you do stem cell treatment for autism and are you based in the uk please get in touch ASAP 07954847546
Shell - 9-Sep-20 @ 10:14 PM
I have a 6 years old autistic child who is not verbal. Please let me know the price for the stem cell therapy and the clinic name
Amal - 28-Apr-20 @ 12:21 AM
Could you send me the address of the Cells Clinic in the UK used to treat Autism,please?
an - 3-Dec-19 @ 11:50 AM
Hi I have 9 yrs autistic son who isnon verbal . I’m interested in stem cells therapy in UK . send me any information and which steam cell use for children.usha
Usha - 28-Nov-19 @ 3:11 PM
Hi I have 10 years ago daughter who is austim . I’m interested in stem cells therapy in UK London send me any information
Susan - 18-Oct-19 @ 10:30 PM
Hi , I have a daughter , 5years and halfand I am really interested in this procedure . Can you please tell me the price ? And where about is this clinic in the UK ? Thank you so much ..:
Alex - 11-Sep-19 @ 10:44 PM
Hi, I want to try stem cell therapy, my son has development delays.
Aiste - 3-Aug-19 @ 6:40 AM
Hi I have a 3yo daughter autistic she is non verbal and delayed in all areas of development I looking for a clinic in the UK to get more info for this sort of Therapy
Rach - 4-Oct-18 @ 9:33 PM
@- I don't think there is a cure for autism. The person just learns how to deal with it better and become more socially aware through learned behaviour.
Andre - 27-Jul-18 @ 2:24 PM
i have been following the discussion.i have a 10 year old boy who has autism.i live in Kenya and i would like to ask whether there are case studies of individuals who have been cured of autism by ScT.If so how much does it cost?Is there a possibility of getting funding because i know it must be very expensive. regards Evelyne
- - 24-Jul-18 @ 8:28 AM
Hi I'm interested in stem cell therapy. Are there any clinics based the in UK London where I can get more information about this. My son is 10yr old and non verbal autistic.
nick - 15-Jul-18 @ 12:34 PM
Hi! I have son 4 years old. Non verbal autist. We are very interested in this therapy. Please gibe any information.
Julija - 10-Jun-18 @ 8:57 PM
I have a 6 year old son with severe ASAP.Advice on any centres in UKthat could stem cell treatment
MARY - 16-May-18 @ 9:58 PM
Hi I'm interested in stem cell therapy. Are there any clinics in UK where I can get the information. Son 6 yr non verbal autistic.
Khan - 9-May-18 @ 5:13 PM
I have a non verbal son with autism who is severely delayed. I am looking in to stem cell treatments. Are there any centres Ithe UK?
Ruh - 4-May-18 @ 9:01 AM
I have Twins with autism,they are 5 Years old. Iwould like to know more about the Steam cells therapy. How much it cost? Where canal i find a clínica? Thanks you
Nuno - 4-Apr-18 @ 4:24 PM
Hello. I am the father of a boy diagnosed with autism. Is 3 years and 4 months old. At birth I did not harvested stem cells. What packages you have and what you guide me on? Makes therapy for 6 months and special nursery school. Makes progress but we want more. Thank you
Ovi - 21-Feb-18 @ 6:21 PM
Hi there , My son is 7 non verbal diagnosed as autistic. I want to know is there any steam cell theropy can cure him ?:
Manu - 5-Feb-18 @ 1:03 AM
Hi, I would like to know if there are any treatment centre in the UK offering stem cell therapy ? Can you send me informations, please? As I would like to know more.
Lau - 16-Jan-18 @ 12:33 AM
I would like to know if there are any treatment centres currently in the U.K. offering stem cell therapy. I have a non verbal daughter with autism.can you please send me as much information as possible
Sam - 9-Jan-18 @ 5:00 AM
i have a4 year old non verbal and servely autistic and am intrested in the stem cell treatment is there any centres in the uk with the best success rates please
Lisa - 1-Jan-18 @ 4:37 PM
i have a 5year old boys who non verbal and servely autistic and am inrrested in stem cell treatment is there any where in the uk
Kelly - 29-Nov-17 @ 1:39 PM
Hi Can you tell me about any UK based centres offering stem cell therapy and costs involved. Which centres have the best success rate and safety record in using stem cell therapy across the world. Please advise Kind regards Mr Sandhu
Pete - 28-Nov-17 @ 4:33 PM
stem cell treatement for my adule sonthank u
camler - 6-Nov-17 @ 3:10 PM
Hi I am interested in stem cell treatment for my 38 years old daughter who is suffering from severe autism, please send me some information about the treatment and cost please ! Kind regards Loanne
Loulou - 25-Oct-17 @ 5:14 PM
Im interested in the stem therapy threatment. How much it cost
Kash - 24-Aug-17 @ 12:05 AM
Hello, I would like to find out more information on stem cell therapy offered in the UK for autism. My son is 5 years old and on the spectrum. His is sevrely autistic and i would appreciate information on any new developments or treatments. Kind regards Ma
Ma - 4-Aug-17 @ 4:27 PM
I would like to know if there are any treatment centres currently in the U.K. offering stem cell therapy. I have a non verbal daughter with autism.can you please send me as much information as possible.
Benjani - 25-Jun-17 @ 8:39 PM
And what about the numerous objections from autistic people that we do not want to be treated nor prevented? I am amazed by what stem cells are able to do and interested in them as a course of treatment for many things, but have an ethical objection to this in particular. I do not want autistics to be prevented. I want us to be born autistic and stay autistic, and you will find many autistic people agree with this. Trying to prevent a certain type of person from existing under the claims of preventing a disorser is borderline or actual eugenics. Autism makes up every aspect of our existence, our personality, our relationships, our thoughts, our behaviors. You are not trying to cure or prevent a disorder- you are trying to cure and prevent a person's entire existence.
C - 2-Mar-17 @ 11:28 PM
Hello ...I have an autistic son who is 7 he is non verbal and I am thinking of stem cell treatment for him.I would like to know if there are any treatment centres currently in the U.K. offeringstem cell therapy .
Ng - 18-Feb-17 @ 2:44 PM
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