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A Rare Side Effects of Stem Cell Therapy: A Case Study

By: Ian Murnaghan BSc (hons), MSc - Updated: 14 Aug 2019 | comments*Discuss
 
Stem Cells Rare Side-effects Tumour

There is no doubt that stem cell therapy holds enormous potential. Unfortunately, this potential also brings with it side-effects, some particularly severe. Such was the case during a therapy that used human foetal stem cells.

The boy in the case suffered from a rare genetic disease known as Ataxia Telangiectasia. This disorder affects many areas of the body and can cause significant disability. The body does not coordinate properly and those who suffer from the disease have a weak immune system as well as problems with their respiratory system.

Unexpected Consequences of Stem Cell Therapy

After undergoing foetal stem cell therapy at a clinic, the boy developed abnormal growths in his brain and spinal cord. The growths were found approximately four years after he had received the stem cell therapy.

While there have been some cases reported where experimentation on rodents resulted in the growth of tumours after stem cell injection, this hadn't been documented in humans after foetal stem cell therapy. Researchers also knew that this risk in rodents could be reduced if the stem cells were differentiated before they were injected. This means that the stem cells were coaxed into the desired body cell for the therapy prior to injection.

Examining a Benign Tumour

But how did the researchers know that in this boy's case, the tumour was indeed from the stem cell therapy? It was all understood after the spinal cord growth was operated on and removed from the boy. Doctors found that it looked like a glioneuronal tumour, which is a benign kind of neural tumour. After more examination, it was determined that this tumour couldn't have stemmed from the boy's own tissues.

A Weakened Immune System

As they tried to understand what went wrong, they considered that the very weak immune system that is commonly seen in Ataxia Telangiectasia could have contributed to the growth. In a sense, the boy's body was an ideal vessel to nourish the growth of this kind of tumour.

In a person who has a healthy immune system, the normal 'checks' on the body would be more likely to prevent a tumour from establishing itself. We have known for some time now that there is the potential for stem cells to trigger the growths of tumours but the reality has been that this is a rarity.

What it Means for Stem Cell Research

Although this rare side-effect of stem cell therapy may be used as part of a case against stem cell research, this would not be a fair approach. Even the authors of the report state that their findings do not imply that we should stop stem cell research.

Rather than put a stop to stem cell research, it has been suggested that we need to spend more time looking at the Safety of Stem Cells. We should try to find out more about what can potentially go wrong and then develop safeguards to reduce any risks associated with stem cell therapies. This way, we can get the most benefits from stem cells while minimising any chances of side-effects along the way.

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Please sir, can STC30 cure Nasal Polyps and for how long can the person use it and how to use it for it to be effective. NB(this person have being operated on twice now and the growth still came back).Now is trying to affect the eyes.
Delight - 14-Aug-19 @ 9:50 PM
Can cartilage at the hip grow back? What is the recommended dosage? How long does it take to start seeing progress?
shajo - 13-Aug-19 @ 11:32 AM
May I know whether the STC30 STEM CELL( which is administered in mouth under the tongue ) has any side effects PLEASE DR.
Ankor - 11-Aug-19 @ 9:25 AM
I have been feeling deep pain along my spinal cord and have diagnosed of t9 fracture. Can you help me?
bmq - 10-Aug-19 @ 12:49 AM
Can STC 30 flush out STD? I need answers please.
Ebere - 8-Aug-19 @ 8:16 AM
I did not get answer or advise on my comments
Bhullar - 7-Aug-19 @ 7:06 PM
I am suffering from stress can STC30 helpme
Non - 5-Aug-19 @ 1:11 PM
I desire to use STC 30 mainly for uprooting fabroid. what is the dosage?
til - 4-Aug-19 @ 4:51 PM
My son suffering from lever infection .in his LFT following is results " Total Bilirubin- 6.3 Direct Bilirubin- 5.4 Indirect Bilirubin- .9 SGOT 206 earlier on 29th July It was 2755 SGPT 916 earlier same was 3170 on 29th July Alkaline phosphate 258bearlier it was 164 on 29th July. Can any body recommend me for giving therapy of Double stemcell
Bhullar - 4-Aug-19 @ 3:46 PM
I want to know if sickler can use stc 30.
T.j - 31-Jul-19 @ 1:56 PM
My brother had accident and had his left leg broken.After the surgery the bones are not healing properly(non union).Later he was told that the bones has been infected hence discharge from a small wound around the affected bone.He's being given antibiotics for the treatment of the infection. Can he use Stem Cell (STC 30) in addition for a better health condition?
Dsoughtout - 20-Jul-19 @ 7:38 AM
My 74 years old father was diagnosed of prostrate Cancer stage 3 and the doctor ordered stc-40 for treatment. Is stc 40 good for such an old man and what prognosis.
Jay - 12-Jul-19 @ 7:52 PM
I am a sickler and I have AVN on my hips, please can stc30 help my condition.
Sonvega1 - 12-Jul-19 @ 6:07 PM
My nephew was diagnosed with colon cancer and started on chemotherapy, he also started to take STC 30, but he complains ofa lot of pain and discomfort especially after putting the powder under the tongue. What could be the problem, should he discontinue STC 30?
blackie - 11-Jul-19 @ 12:54 PM
I'm having stomach pain can and low rips pain also can STC work for me?
Kent - 10-Jul-19 @ 5:16 PM
Please a friendis now blind as a result of glaucoma. Can STC 30 help cure him?
Precial - 6-Jul-19 @ 6:04 PM
doctor told me my ovaries can not develop a child can stem-cell work
stella - 20-Jun-19 @ 10:33 AM
Can this medicine cure Hyper active thyroid, with visible elevation of under the chin or neck?
Sussiebee - 31-May-19 @ 8:49 AM
My wife was diagnosed bilateral optics atrophy and later advanced glaucoma which resulted in blindness Can the stem cell work for the restoration of the eyes. Thanks.
Marc - 2-May-19 @ 8:14 PM
My brother had accident and had his left leg broken.After the surgery the bones are not healing properly(non union).Later he was told that the bones has been infected hence discharge from a small wound around the affected bone.He's being given antibiotics for the treatment of the infection. Can he use Stem Cell (STC 30) in addition for a better health condition?
Delaso - 18-Mar-19 @ 5:06 PM
Some lab tests were run on me and it was noticed that I have lots of cholesterol and I want to know what to do next
Mavis Osei Boateng - 11-Nov-18 @ 3:31 PM
Hello, I have meningioma grade II Atypical, can i take purtier placenta. It was removed last 2016. I am partially paralyzed. Looking forward for your reply. Thank you
Mai - 3-Nov-18 @ 8:21 AM
I have Spinal Cord Injury(T7-T8), with 3rd degree pressure sore on both behind, and a diabetic. May I ask, what health benefits will I gain if I take putier placenta? I'm 58 yrs old, male.
Arrhur - 3-Nov-18 @ 12:32 AM
I am an onco patient. I have neshophyringe cancer. I got this in 2013. I am doing well as my doctors suggest.Is it safe to take ST30. Plz suggest
Ningombam Thoithoi S - 28-Oct-18 @ 5:39 AM
My brother in law used Purtier Placenta he has a high blood pressure and is diabetic.He often gets dizzy,nauseous,vomits a lot. At the beginning he regained his strength rapidly.After a few weeks his creatinine rouse up to the extent that it went up to his brain.He stopped using it and was having a dialysis 3x a week. Same thing happened with my friends mom,she was at the ICU drank purtier placenta.Got discharged in the hospital after 2 days of drinking the product.Made her condition worst / severe after 2 weeks and died.
K - 24-Oct-18 @ 6:24 PM
Am suffering from a kidney injurymy doctor did not recommend stem cell for me but my mom is a nurse and she gives it to me is it safe for me will I get well
Grace - 12-Oct-18 @ 1:25 PM
Is it normal to miss a menstrual period after stemcell stc30 because I'm a whole month late and have taken numerous pregnancy test and all negative
Kirsten - 28-Sep-18 @ 9:26 PM
For real i have discovered that this medicine has really helped so many people. And many people must be introduced to this medicine because you can not enjoy life when you are sick. Health first.
Chiso - 20-Sep-18 @ 6:23 AM
Try Purtier Placenta. It is an oral type of stem cell or live cell therapy that helps people who suffer from heart problems, cancer, diabetes, parkinsons, autism and more. Search for the product and watch you tube videos showing testimonials on how this product helped them.
aileen - 13-Sep-18 @ 8:26 AM
My doctor recommends Stem cell therapy for me all thou I am basically a healthy Man of 79 yrs ol. The reason he gives is Stem cell therapy will keep me healthy for a longer period of time. I am not sure of what to think.Naturally I want to live healthy as long as possible.What would you do.? TY
Daniel Nociaro - 28-Aug-18 @ 4:07 AM
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