Home > Stem Cell Therapy > Peripheral Blood Stem Cell Harvest

Peripheral Blood Stem Cell Harvest

Author: Ian Murnaghan BSc (hons), MSc - Updated: 22 July 2014 | commentsComment
Stem Cells Peripheral Blood Harvest

A peripheral blood stem cell harvest is a technique used to restore a person's blood cells after they have been damaged by chemotherapy or radiation. The procedure is often used to treat patients with either leukaemia or lymphoma cancer. Because the chemotherapy or radiation treatment damages healthy cells alongside cancer cells a patient requires a viable source of blood-forming cells. Stem cells are able to generate the white blood cells, platelets and red blood cells that are important for functions such as oxygen transport, clotting and immunity.

What Types Are There?
There are three types of transplants that may be performed for a peripheral harvest:
  • Autologous: a patient receives his or her own stem cells.
  • Allogeneic: a patient receives stem cells from someone else-either a relative or an unrelated donor.
  • Syngeneic: a patient receives stem cells from an identical twin.
How Are The Peripheral Blood Stem Cells Obtained?
The stem cells utilised in this procedure are obtained from the bloodstream in a process called apheresis. In the preceding week before apheresis is performed, a donor receives drugs to increase the number of stem cells in his or her bloodstream. During apheresis, the donor's blood is removed, usually through the arm, and it flows through a machine that removes the stem cells. The blood then flows back to the donor while the extracted stem cells are then frozen until they are transferred to the recipient. The process usually lasts approximately five hours.

How Are Peripheral Blood Stem Cells Given To The Patient?
The patient is treated with either radiation or strong cancer drugs, before receiving stem cells through an intravenous line. After the stem cells are transplanted into the patient, they move from the bloodstream to the bone marrow. It is here that they produce healthy white blood cells, red blood cells and platelets. The process is called engraftment and it generally occurs over the two to four weeks following stem cell transplantation. Physicians will follow a patient's progress by observing blood counts on a regular basis to ensure that the engraftment is successful. A complete recovery is much more long-term, however, and immune functioning can take months to years before it is fully recovered. Sometimes, bone marrow aspiration is performed, where a physician samples a small amount of bone marrow to provide a detailed assessment of the patient's progress.

Advantages of Peripheral Blood Stem Cell Harvest
Although traditionally, all stem cell transplants that were initially performed were bone marrow transplants, peripheral blood stem cell transplants are now commonly used. It is often the case that more stem cells can be harvested from peripheral blood as opposed to bone marrow. In addition, the procedure for extracting cells from the donor is less taxing and complicated than a bone marrow stem cell harvest. Even more beneficial is the fact that the recipient's blood count tends to replenish much more quickly in comparison with a bone marrow harvest.

Therapies such as peripheral blood stem cell harvests are often life-saving. For those who have suffered from cancer or know someone who has battled the disease, stem cell treatments have provided a better chance of remission from the disease. Further research into new treatments as well as improving older ones will ensure that we stay on the path to a cure for cancer.

You might also like...
Leave a Comment, Ask for Advice or Share Your Story...
very nice article.please i want to know the name of machine used to separate stem cells from epepherial blood and price for machine and kit.please help me soon.thank you.
aminlab - 22-Jul-14 @ 1:32 PM
binnu - 23-Jun-14 @ 1:46 PM
An absolutely brilliant article. Finally explained in plain english!! Thank you!
holly - 30-Mar-11 @ 10:58 AM
Leave a Comment, Ask for Advice or Share Your Story...
(never shown)
(never shown)
(never shown)
(never shown)
Enter word:
Our Quick Links
Latest Comments
  • majoni
    Re: Treatments with Stem Cells
    sir, please give me information that, one of my patient , before 5 years througg an accident he can't walk . Because he is suffering…
    29 July 2015
  • MaggieMay
    Re: Stem Cells That Don't Age
    I have been told my right hip needs replacing and the pain has gotten pretty bad what would be the cost for my hip,MAT I have…
    29 July 2015
  • dipaolo
    Re: Stem Cells and Same Sex Reproduction
    So far from nature. It's horrendous. Mad-science is no longer a thing of fantasy.
    24 July 2015
  • nav
    Re: Benefits of Stem Cells
    My father is diabetic patient and have puss infection. Right now, he is not able to move much. His memory and body is weak now.there is…
    23 July 2015
  • selavee
    Re: Ovarian Function and Stem Cells
    47 with hypothyroid & menopause at 46 tried to get pregnant after the both of my 7 year old born in 2008. No luck. Please…
    22 July 2015
  • Tony
    Re: Stem Cell Scandal: A Case Study
    I have been contemplating whether to have a stem cell treatment for my 15 year old Autistic daughter. I have been in touch…
    21 July 2015
  • Ceris
    Re: Stem Cells to Treat Blindness
    Hello, my father has detached retinas and has just had an eye stroke. He will lose the remainder of his sight over the next few…
    21 July 2015
  • Chalky
    Re: Restoration of Paralysis, can Stem Cells Help?
    My son-in-law suffered a Brain Stem Stroke in March 2013. From a position of near death and Locked-…
    19 July 2015
  • sukie
    Re: Stem Cells for Stroke Victims
    I am writing this on behalf of an elderly gentleman who had stroke around 7 years ago, he would like to know if these stem cells…
    16 July 2015
  • Ali
    Re: Benefits of Stem Cells
    Hi.. i have fshd. It has effected my right hand and shoulder. I am not able to raise my right hand more than 90° and my right scapula bone…
    15 July 2015
Further Reading...
Our Most Popular...
Add to my Yahoo!
Add to Google
Stumble this
Add to Twitter
Add To Facebook
RSS feed
You should seek independent professional advice before acting upon any information on the ExploreStemCells website. Please read our Disclaimer.